name: guanfacine (GWAHN
class: central alpha agonist
All FDA warnings are at
the end of this fact sheet. Please consult them before taking this
are Intuniv®/Tenex® and what do they treat?
is a prescription medication that is used to treat attention-deficit
hyperactivity disorder (ADHD) in individuals between 6 and 17 years
of age. Guanfacine is also used to treat blood pressure in both
children and adults.
of ADHD interfere with an individual’s ability to function at
school or work or in social settings and include:
(e.g., making careless mistakes, losing things necessary for tasks)
(e.g., inability to sit still)
(e.g., interrupting or intruding on others)
person may have severe inattention without hyperactivity or
used in addition to non-medication treatments to manage ADHD
is the most important information I should know about
some symptoms may improve within days of starting guanfacine, it may
take several weeks before you notice the full benefits of the
there specific concerns about Intuniv®/Tenex® and pregnancy?
you are planning on becoming pregnant, notify your healthcare
provider so that he/she can best manage your medications. People
living with ADHD who wish to become pregnant face important
decisions. There are no well-controlled studies of guanfacine use in
pregnant women. Animal studies did not demonstrate evidence of fetal
harm. It is important to discuss the risks and benefits of treatment
with your doctor and caregivers.
breastfeeding, caution is advised since guanfacine does pass into
should I discuss with my healthcare provider before taking
of your condition that bother you the most
you have thoughts of suicide or harming yourself
you experience side effects from your medications, discuss them with
your provider. Some side effects pass with time, but others may
require changes in the medication.
other psychiatric or medical problems you have, including heart
other medications you are currently taking (including over the
counter products, herbal and nutritional supplements) and any
medication allergies you have
non-medication treatment you are receiving, such as talk therapy or
substance abuse treatment. Your provider can explain how these
different treatments work with the medication.
you are pregnant, plan to become pregnant, or are breast-feeding
you drink alcohol or use drugs
should I take Intuniv®/Tenex®?
is usually taken 1-2 times per day. Guanfacine can be taken with or
without food. However, taking it with a high fat meal can increase
absorption and may increase effects.
dose usually ranges from 1 mg to 4 mg per day. Only your healthcare
provider can determine the correct dose for you.
release tablets (Intuniv®)
should not be crushed, chewed or divided. Swallow the tablet whole.
happens if I miss a dose of Intuniv®/Tenex®?
you miss a dose of guanfacine take it as soon as you remember, unless
it is closer to the time of your next dose. Discuss this with your
healthcare provider. Do not double your next dose or take more than
what is prescribed.
should I avoid while taking Intuniv®/Tenex®?
may cause dizziness or drowsiness, especially when first starting the
medication. Make sure you know how you react to the medication before
you drive, operate machinery, or participate in other activities that
may be dangerous if you are not alert.
drinking alcohol or using illegal drugs while you are taking this
medication. They may decrease the benefits (e.g., worsen your
condition) and increase adverse effects (e.g., sedation) of the
happens if I overdose with Intuniv®/Tenex®?
an overdose occurs call your doctor or 911. You may need urgent
medical care. You may also contact the poison control center at
with guanfacine may cause sleepiness, dizziness, low blood pressure
and slow heart rate.
specific treatment to reverse the effects of guanfacine does not
are possible side effects of Intuniv®/Tenex®?
drowsiness, dizziness, headache, irritability
stomach pain, dry mouth, constipation and decreased appetite
there any risks for taking Intuniv®/Tenex®for
long periods of time?
are no known problems associated with long term use of guanfacine.
other medications may interact with Intuniv®/Tenex®?
following medications may increase the levels and effects of guanfacine:
following medications may decrease the levels and effects of guanfacine: rifampin (Rifadin®),
and phenytoin (Dilantin®)
may increase the levels and effects of: valproic acid (Depakene®,
long does it take for Intuniv®/Tenex® to work?
you may experience beneficial effects from guanfacine within a few
days of starting the medication, it often takes several weeks to get
the full effect of the medication. Your healthcare provider may also
need to adjust gradually the dose to find the dose that works best
by the College of Psychiatric and Neurologic Pharmacists
not have any Black Box Warnings