National Alliance on Mental Illness
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©2009
Bipolar Research Studies
Schizophrenia and Bipolar Disorder Family Genetic Research Study
Age: 15-65
Location:
The University of Chicago along with the University of Illinois at Chicago are seeking individuals in the Chicago area who suffer from Schizophrenia, Schizoaffective Disorder, or Bipolar Disorder with psychotic features with available immediate family members to participate in our genetic study. Family members do not have to suffer from mental health symptoms to participate. The overall goal of this research is to improve our understanding about the biological causes of these illnesses so that we can develop better treatments to improve and eventually restore the lives of patients who suffer with them. This study is overseen at the
Participants will undergo a 2-4 hour diagnostic interview at the
Contact the study line at 866-51-GENES or 773-834-3560 for more information. More information is provided on our website: http://www.ucfamily.org/familystudies/main.html.
Posted: 1 September 2009
Longitudinal Study of Bipolar Disorder
Age: 18-65
Location: Michigan
Bipolar and Healthy Control Research Participants Needed
The Bipolar Research Group at the University of Michigan Department of Psychiatry and Depression Center, is seeking individuals ages 18-65 with a diagnosis of bipolar disorder without a history of schizophrenia. Investigators also seek healthy controls with no diagnosis. The purpose of the study is to identify potential illness patterns in bipolar disorder. This will be done through the analysis of genetic information and continued observation for five years. Study participation involves an initial visit consisting of a structured interview, cognitive testing, questionnaires, and a blood draw for genetics and biomarkers, after which interviews and questionnaires will be performed at various time intervals. Participants are compensated for their time. For more information contact us at: 877-UM-Genes (877-864-3637) or BPresearch@umich.edu.
Posted: 1 September 2009
Portraits of Leaders who cope Successfully with their own Bipolar Disorder in the Workplace
Age: 18+
Location: Nationwide
This research is designed to improve the quality of work lives for individuals who struggle with bipolar disorder in the workplace. The findings from this study may help many unemployed individuals who suffer from bipolar disorder find hope that it is possible for them to succeed in the workplace. In addition, through the interview process, participants will have a chance to reflect on their own work experiences, which may enhance self-discovery, personal growth, and decision-making.
Participation in this study will involve:
- Engaging in an in-depth interview in person or via phone. The interview will be approximately sixty (60) but no more than ninety (90) minutes.
- Engaging in two to four optional follow-up interviews of no more than 60 minutes in duration.
- It is possible that interviews may exceed the time allotted by mutual consent only.
Participation Eligibility Criteria:
Participants must meet all of the following criteria:
- Individuals who have a psychiatric diagnosis of bipolar disorder type I or II and are in middle management or higher within a for-profit or non-profit organization.
- Individuals who receive care and medical treatment for bipolar disorder from a psychologist, psychiatrist, primary care physician or other healthcare professional.
- Individuals who have been in their current organization for at least 3 years, regardless of job title.
- Individuals who have a stable work history in the past seven years (at least 2 years history with any past employer, regardless of job title).
- Individuals who have the authority to make decisions about how to do the work.
- Individuals who have fiscal responsibility (i.e., budgetary control) in his or her current role and have at least one direct report.
If interested in participating in this study, individuals may contact Maria Chang-Calderon to enroll via phone at (925) 922-2062 or via email mcc1208@sbcglobal.net.
Posted: 1 September 2009
Spouses and Partners of People with Bipolar Disorder
Age: 18+
Location: Nationwide
Spouses/Partners of people with Bipolar Disorder are needed for a research study about your relationship experiences. This research is being conducted by a student in the Ph.D. program in clinical psychology at the California School of Professional Psychology,
Posted: April 15, 2009
Schizophrenia and Bipolar Disorder Family Genetic Research Study
Location:
Age: 15-65
The
You may be eligible to participate in the study if you meet these conditions:
- Age between 15-65 years
- Diagnosis of schizophrenia, schizoaffective disorder or bipolar disorder (with psychosis)
- Have at least one biological first-degree relative, i.e., a sister, brother, mother or father willing to participate. The relative does not need to be diagnosed with a psychiatric disorder but it is ok if they are
- No serious medical, neuro-opthalmological or neurological illness (e.g., cancer, seizure disorders, encephalopathy)
- No current substance abuse (within past 3 months) or past history of substance dependence (within 6 months or extensive history)
- No ferromagnetic objects lodged in the body
Participation involves:
- Clinical interviews to evaluate diagnosis and gather other personal information
- Neuropsychological Tests to examine thinking abilities such as attention and memory
- Electroencephalography (EEG)/Sensory Gating tests to measure brain activity in response to sounds
- Eyetracking tests to measure eye movements and visual attention
- MRI to measure brain structures and function
- Blood sample for DNA (genetic) studies
- Urine sample to screen for drugs and pregnancy
The total amount of time it takes to complete the study is approximately 14-16 hours. Transportation can be provided if needed. All participants will be compensated for their time.
For more details, call our research coordinator, Jennifer Jones, at 410-402-6823
Posted: April 15, 2009
Child Bipolar Disorder Study
Age: 10-17
Location: Ohio
Is your child or teen being treated for bipolar I disorder and still experiencing symptoms?
Your child or teen may qualify to participate in a clinical research study in your area evaluating an investigational medication as a potential add-on treatment for bipolar I disorder in children and teens ages 10-17. Children and teens enrolled in this study may continue on their current prescribed medications. Each participant will receive comprehensive, study-related evaluations and investigational study medication at no cost. Compensation for time and travel may also be provided to those who qualify. Please call The Ohio State University, Department of Psychiatry Clinical Research Office at 614-293-7109 or e-mail clinicaltrials@osumc.edu to learn more.
Posted: February 17, 2009
Bipolar Genetic Family Research Study
Age: 18+
Location: Nationwide
We are seeking individuals who have been diagnosed or have all the symptoms of bipolar disorder, who also have family members with depression or mania. Our study asks individuals suffering from Bipolar Disorder and their family members suffering from mood disorders to undergo a 2-4 hour diagnostic interview and provide a small blood sample. Each participant will be compensated $75. Travel is not required. We can accommodate participants from all over the country. The study is ongoing until 2010. Please call 866-51-GENES (866-514-3637) or e-mail Ben Romanos at bromanos@yoda.bsd.uchicago.edu. You may also visit us at http://www.ucfamily.org for more information.
Posted: 25 July, 2008
Are you living in the shadow of bipolar depression?
Age: 18+
Location:
As a person with bipolar 1, you know what it’s like to live with the darkness of depression. So you may want to know about this clinical research study examining an investigational drug for bipolar depression compared to placebo, an inactive substance, when used in combination with a mood stabilizer, if you:
-Are at least 18
-Have been diagnosed with bipolar 1 and are experiencing a depressive episode
-Have a history of at least 1 manic or mixed episode
Participation may last up to 12 weeks, and includes study-related care and monitoring from specialists in bipolar 1, access to a mood stabilizer, and potential access to the investigational medication, all at no cost.
To learn more, please contact Judith Engelman, MD at: Dedicated Clinical Research,
Posted: 8 July, 2008
Norepinephrine and Impulsivity
Do you or someone you know suffer from:
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Excessive energy?
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Inability to sleep?
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Spending too much money?
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Extreme irritability?
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Rapid speech or thoughts?
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Severe or frequent mood swings?
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Impulsive behavior?
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Been diagnosed with bipolar disorder or recently hospitalized?
If you answered "yes" to any of these questions, you may qualify for an ongoing research study of bipolar disorder. The University of Texas Mental Sciences Institute is now seeking individuals to participate in a research study on bipolar disorder. Qualified participants will be compensated for their time. For more information please call (713) 500-2635.
Posted: 3 December 2007
Study of Lithium for the Treatment of Pediatric Mania
Is your child between 7-17?
Does s/he have excessive energy?
Irritability?
Mood swings?
Ever been diagnosed with Bipolar I disorder?
If so, your child may be eligible to participate in a clinical research program and receive study related examinations, lab tests, and medication at no cost from a doctor specialized in adolescent mental illness.
There may be an enrolling site near you. Please see below for sites and contact information.
University Hospitals Case Medical Center, Cleveland, OH-- Dr. Robert Findling (216) 844-3922
Cincinnati Children's Hospital, Cincinnati, OH-- Dr. Robert Kowatch (513) 636-0160
The Zucker Hillside Hospital North Shore, Long Island, NY-- Dr. Vivian Kafantaris (718) 470-8362
The University of Illinois, Chicago, Chicago, IL-- Dr. Mani Pavuluri (312) 413-1722
University of North Carolina at Chapel Hill, NC-- Dr. Lin Sikich (800) 708-0048
Children's Hospital and Regional Medical Center, Seattle, WA-- Dr. J. McClellan (206) 987-3399
Cambridge Hospital, Cambridge, MA-- Dr. Jean Frazier (781) 306-8630
Posted: 3 December 2007
BIPOLAR STUDY
Study Location: Manhattan and Brooklyn, NY
Age: 18 - 65
If you have been diagnosed with Bipolar I Disorder and are currently feeling depressed, you may qualify for a study being conducted by the Social Psychiatry Research Institute (SPRI) of an investigational medication for Bipolar I Disorder. Eligible participants must currently be taking a mood stabilizer. The purpose of this study is to evaluate the effectiveness of an investigational medication when taken in combination with a mood stabilizer. Patients may not be currently abusing or dependent on alcohol or illicit drugs. Study participants will attend regular visits over 10 weeks and receive study medication and medical evaluations at no cost. Health insurance is not required. If interested in this study, you can apply online at www.spristudy.com, email us at studyinfo@spristudy.com, or call 1-888-345-7774.
Posted: 28 November 2007
Rewards Study
Have you been told that you have: MANIA, MANIC-DEPRESSION, or BIPOLAR DISORDER?
The University of Miami is conducting a study locally to look at how moods relate to thinking. The study involves an interview about mood changes and different computer tasks and games. The purpose of this study is to understand how people with and without bipolar disorder think about potential rewards. Participants will be paid $25 per hour.
To learn more, please contact: The Rewards Study at 305-284-1587.
Posted: 16 October 2007
Acute Pharmacotherapy of Late-Life Mania- Bipolar Research Study
With aging, many people with bipolar disorder or manic-depression continue to experience mood swings. Some people develop these symptoms for the first time. Although effective treatments exist, these problems may remain undiagnosed and untreated or under-treated.
The Weill Cornell Institute of Geriatric Psychiatry is currently conducting a 9-week research study comparing the benefits and side effects of lithium and valproate (divalproex) in the treatment of late-life bipolar disorder.
Services are available for individuals age 60 and older who are currently experiencing an elevated mood and who meet study eligibility criteria. This study is being conducted at 8 research sites and sub-sites in the U.S. and Canada. For a free, confidential bipolar screening or for more information about our Bipolar Treatment Study, please call (914) 997-4331 or 800-NYP-1902.
Posted: 6 September 2007
Research Study Trying to Improve Depressive Symptoms Quickly
Several medications are effective for treating depression; however, they take weeks or months to achieve their full effects. NIMH (the National Institute of Mental Health) is studying whether a drug can cause a rapid antidepressant effect in patients with bipolar or unipolar depression. The study also tries to see if it can sustain the results with another medication in certain patients. Understanding how this works may help us understand depression and design better antidepressants. NIMH is seeking people ages 18-65 with depression (unipolar or bipolar) who are:
- Free of other serious medical conditions
- Willing to participate in a minimum of a 12-day inpatient stay
Research medications provided free of charge. Compensation and transportation reimbursement is provided.
Atendemos pacientes de habla hispana.
Call: 301-496-5645 (TTY: 1-866-411-1010) or Libby Jolkovsky, M.S. at 301-402-9347 or http://patientinfo.nimh.nih.gov; for other studies: www.clinicaltrials.gov
Do you have bipolar disorder (also known as manic depression)?
We are studying the genetics of how bipolar is transmitted within families. We are looking for subjects who have the disorder to do an interview and blood draw. Compensation provided. Call 888-820-3395, study coordinator Diana Marta, RN, BSN.
Bipolar Depression Clinical Trial - Have you been diagnosed with bipolar disorder?
Do you feel that medications have not helped your depression? If so, you may qualify for an 8-12 week study for treatment of bipolar depression. We are looking for adults between the ages of 18 and 75, who are depressed, currently in treatment with an outpatient psychiatrist and are taking a mood stabilizer. Volunteers will receive free study medication, laboratory tests and will be compensated for their participation. For more information, please call (410) 502-2334. Principal Investigator: Jennifer Payne, M.D.
Bipolar Disorder Study - Signs and Symptoms:
Feeling down and depressed? Lost interest in your normal activities? Do you have uncontrollable mood swings, trouble sleeping, or difficulty concentrating? Do you experience highs and lows? If you or someone you know is experiencing any of these symptoms, you may be suffering from Bipolar Depression (also known as Manic Depression). Daniel D. Anderson, M.D., is conducting a research study for people with Bipolar Depression. If you qualify, you may be eligible to participate in a study testing the effectiveness of a research medication for the treatment of Bipolar Depression at no cost to you. If you would like additional information regarding this study and are between the ages of 18 and 75, please contact Dr. Daniel Anderson at (310) 891-0106.
Treating Depression in Patients with Bipolar Disorder:
GlaxoSmithKline (GSK) is sponsoring clinical research studies to evaluate the effectiveness of a medication for treating depression in patients with bipolar disorder. This medication is currently approved by the FDA for the maintenance treatment of bipolar disorder; however, less is known about its use for acute treatment of bipolar depression. Patients are randomly assigned to receive either the medication or a placebo for eight weeks. If eligible, patients will come to the clinic approximately once a week during the treatment phase of the study, and once more for a follow-up visit after the treatment. To be eligible, a patient must be at least 18 years old, experiencing depression, and have a diagnosis of bipolar disorder. There are no costs to the patient for study medication, study visits or study procedures. Participation is entirely voluntary and patients may withdraw from the study at any time for any reason. Visit BipolarDepressionStudy.com or Veritasmedicine.com (click bipolar disorder then find clinical trials).
Siblings with Bipolar Disorder:
National Institute of Mental Health, Intramural Research Program, National Institutes of Health, Department of Health and Human Services. Looking for families with two or more siblings with bipolar illness. Diane Kazuba, toll-free, at 1-866-NIH-GENES (1-866-644-4363), or email: kazubad@intra.nimh.nih.gov
Adults with Bipolar Disorder and Depression
There are opportunities to participate in clinical trials exploring the research effects of novel therapeutics compared to placebo for the treatment of depression and bipolar disorder. Several of these trials look at treatment-resistant mood disorders. Volunteers over the age of 18 may be eligible. The studies are conducted at the National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, in Bethesda, Maryland. Atendemos pacientes de hable hispana. Call 301-496-5645 or 1-866-627-6464 (TTY: 1-866-411-1010).
Child and Adolescent Bipolar Disorder Study
The National Institute of Mental Health is seeking boys and girls ages 6 to 17 to participate in a study of bipolar disorder in children and adolescents. The study includes a five-day outpatient assessment and infrequent research follow-up visits over four years at the NIH Clinical Center in Bethesda, MD.
Participants must be:
- In treatment with a psychiatrist for bipolar disorder
- On stable medications for the first 6 weeks of the study
- Able to fill out daily self-rating forms and cooperate with study procedures (including genetics studies, MRI, psychological testing, and others)
A thorough evaluation at NIMH is provided free of charge. Travel and lodging expenses are paid for by NIMH. For more information, call 301-496-5645 (TTY: 1-866-411-1010).
Children and Adolescents with Bipolar Disorder
The National Institute of Mental Health is conducting a study for treatment-resistant bipolar disorder.
Participants will receive:
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Clinical and psychological assessments (including an inpatient assessment during which children will be withdrawn from medication)
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Treatment with clozapine or placebo
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Brain imaging (no radiation)
Participants must:
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Be between the ages of 8 to 17 with bipolar disorder
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Not have done well on lithium, sodium valproate, carbamazepine, and at least one of the newer neuroleptics, as well as a combination of two of these medications
All procedures are free of cost. Travel expenses are paid for. Call Robinder Bhangoo, M.D., or Ellen Leibenluft, M.D., at (301) 496-8381 or (TTY 1-866-411-1010).
Adolescent Bipolar I Study
Participants are needed for a new adolescent Bipolar I Disorder research study of an atypical antipsychotic investigational medication known as Olanzapine. Teenagers must be between ages 13-17 and be diagnosed with Bipolar I Disorder, currently displaying an acute manic or mixed episode, or displaying the symptoms of Bipolar I Disorder. To learn more about participating in this research study, please visit www.teenmentalhealth.net or call toll free 1-866-874-2516.
Bipolar Depression Research Study
This is a six-month Phase IV study comparing two marketed medications in the treatment of bipolar depression. If you have been diagnosed with Bipolar Depression (also called Manic Depression) and are currently depressed with symptoms such as:
- Sadness
- Loss of interest
- Difficulty sleeping
- Lack of energy
- Changes in appetite
You may be eligible to participate in an investigative medication research study comparing two active medications for the treatment of Bipolar depression.
Participants should be 18 to 60 years old, currently depressed, have experienced at least one manic episode in their lifetime, and be in reasonably good health. Participants will have to undergo blood work, urine drug screening and EKG.
Study related tests and evaluation provided at no cost. $20 per visit provided for travel expenses.
Call (888) 317-6262 for more information.
Recurrent, Early Onset of Depression
NIMH-funded multi-site study of recurrent, early onset depression is looking for families with bipolar illness. The first major depression must have occurred before age 30 in one sibling and before age 40 in the other.
- University of Iowa: Sandra Boutelle, 1-877-578-8845 (toll-free) or 1-319-353-4347, email: boutelle@blue.weeg.uiowa.edu
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University of Pennsylvania: Kathleen Murphy-Eberenz, 1-877-407-9529 (toll-free) or 1-215-746-5153, email: kme@mail.med.upenn.edu
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University of Pittsburgh: Wendy Zubenko, 1-877-485-7568 (toll-free) or 1-412-246-6530, email: wzubenko+@pitt.edu