Obsessive-Compulsive Disorder Research Studies

A Pediatric Study of Obsessive Compulsive Disorder (OCD)

Age: 8-17
Location: Massachusetts

The Pediatric Psychopharmacology Research Unit at Massachusetts General Hospital (MGH) is conducting a research study that focuses on children affected by Obsessive Compulsive Disorder (OCD). The researchers are looking for children to participate in a pilot study to find out whether the antibiotic Seromycin, or D-Cycloserine (DCS) can boost the effectiveness of cognitive behavioral therapy (CBT), particularly with regard to fear extinction in the treatment of pediatric OCD.

The current study is enrolling children ages 8-17 years old who have OCD. The participation of one parent to accompany the child to all study visits is required. Subjects will randomly (that is, by chance) receive DCS or a placebo (no active drug). This study will involve 10 CBT sessions over 8 weeks. In addition, there will also be 3 assessment visits, which involve structured clinical interviews, blood drawings, a full physical exam, a pregnancy test (if applicable), and the monitoring of participants’ safety. Highly trained clinicians will conduct CBT, and an expert in the field of OCD will conduct all assessment visits.

If a child meets the criteria and you are interested in learning about this study, please call the Pediatric Psychopharmacology office at 617-503-1436, or send an email to eamancuso@partners.org.

Posted: 13 February, 2009

Obsessive Compulsive Disorder/ Body Dysmorphic Disorder Study

Age: 18-65
Location: San Diego

The UCSD OCD Program is looking for individuals with Body Dysmorphic Disorder (BDD) and/or Obsessive Compulsive Disorder (OCD) to participate in a research study providing 12 weeks of medication treatment, brain imaging, and neuropsychological testing. If interested please review our web site: http://psychiatry.ucsd.edu/OCD_BDDStudy.html.

Posted: 14 October 2008

A Family Genetic Study of Tourette Syndrom (TS), Attention Deficit Hyperactivity Disorder (ADHD), and Obsessive Compulsive Disorder (OCD).

The Center for Human Genetic Research with Massachettes General Hospital (MGH) is conducting a research study that focuses on families affected by Tourette Syndrome (TS), Attention Deficit Hyperactivity Disorder (ADHD), and Obsessive Compulsive Disorder (OCD). The Center's researchers are looking for common behavioral straights, such as attentional difficulties and impulsivity, which may be shared by these conditions. If found, researchers want to determine whether these traits are heritable, that is, can be passed down from parents to children. We hope that the information we learn will eventually help researchers to develop better treatments for these conditions.

The current study is enrolling families in which there is at least one child between the ages 6 to 21 who has TS, ADHD, and/or OCD, or any combination of these conditions. The participation of both parents, brothers and sisters is desired. Subjects will complete interviews, questionnaires and assessments examining areas, such as attention, impulsivity, problem-solving, visual-spatial skills, and sensory sensitivity. Researchers will also collect a blood or saliva sample for DNA testing. Study participation is strictly voluntary and may require 3-6 hours per person for the completion of all study tasks. NOTE: Study visits can be at MGH or in your home.

Families coming to MGH will have parking and meal expenses paid for them. Upon completion of all study tasks, families will be paid $100 for their participation. If a family meets the criteria and are interested in learning about this study, please call the Genetic Family Study at 1-800-471-2730, or send an email to cillmann@partners.org. Please visit our website at www.ts-adhd-ocd.org.

Posted: 24 August 2007

Treatment of Obsessive-Compulsive Symptons.

A new research study is being conducted at Nathan Kline Institute in Rockland County, New York, by William Greenberg, M.D. Thirty-two volunteers, ages 18 to 55, are being sought to help determine if adding an extra daily oral supplement to their current treatment will help relieve Obsessive-Compuslive symptoms. The main part of the study is a 12 week double-blind period involving monthly visits, during which participants will remains on their current treatment (medication and/or psychotherapy), and in addition take either the investigational study treatment or an inactive placebo. After this 12 week double-blind phase, all participants who wish to continue with the study will definitely receive the investigational treatment (no placebo) for another 12 week period. This study is supported by a research grant awarded from the Obsessive-Compulsive Foundation. Those interested should call Joanna Doerfer at (845) 398-2183 for more about eligibility criteria and other information.

National Institute of Mental Health, Intramural Research Program, National Institutes of Health, Department of Health and Human Services.

Looking for families with two or more siblings with OCD. Diane Kazuba, toll-free, at 1-866-NIH-GENES (1-866-644-4363) or email: kazubad@intra.nimh.nih.gov