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Intravenous Ketamine Effective As Quick-Acting Antidepressant With Mild, Brief Side Effects

Nov 18 2019
Ketamine has been shown to relieve depressive symptoms within hours of a single intravenous (IV) treatment. To develop a new therapy based on ketamine, researchers must account for potential side effects — especially given the drug’s history of recreational misuse. A new report analyzing data from five clinical trials conducted at NIH over 13 years shows that common side effects of a single IV treatment were mild and lasted only a few hours. This encouraging result supports ongoing research to develop practical, quick-acting antidepressants. To learn more, please visit the NIMH website.