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Antibody Therapy May Represent New Way to Treat Obsessive-Compulsive Disorder

Apr 21 2020
Most treatments for conditions like anxiety, depression and obsessive-compulsive disorder (OCD) target chemical activity in the brain, but a new study supports targeting the immune system. Researchers discovered that mice with high levels of a protein called Immuno-moodulin, or Imood, experienced significant anxiety. Treating those mice with an antibody against Imood caused the symptoms to disappear in a few days. Researchers have now shown that people with OCD have levels of Imood up to six times higher than unaffected people and are working to develop an antibody therapy for future study. To learn more, see the study in Brain, Behavior, and Immunity.