Stopping Antidepressants Raises Relapse Risk

Stopping Antidepressants Raises Relapse Risk
Posted on Sep 29 2021
U.S. News & World Report

People who stop taking antidepressants after long-time use may face a high likelihood of depression relapse, a new study suggests. Researchers found that among patients who stopped taking their antidepressants because they felt well, 56% relapsed within a year compared with 39% of patients who stayed on medication. "Often, patients want to know: How long do I need to be on this medication?" said Dr. Christine Crawford, associate medical director of NAMI. "This study helps equip psychiatrists in talking to patients about the risk of relapse if they stop taking their antidepressant," said Crawford, who was not involved in the trial. Crawford said people who are receiving psychological counseling and have strong relationships with family and friends are likely to do better after stopping antidepressants than people who lack those support systems. For many patients, Crawford said, the medications are simply an effective way to treat a chronic medical condition — just as people take medications for high blood pressure or diabetes. "Medication is just one piece of the puzzle," Crawford said. But, she added, antidepressants may help "lighten the load" of depression, making it easier for people to manage the stresses in their lives.