NAMI HelpLine

Psychosis

Psychosis involves disruptions to a person’s thoughts and perceptions that make it difficult for them to recognize what is real and what isn’t. Many people think of psychosis as a break with reality. These disruptions are often experienced by seeing, hearing and believing things that aren’t real or having strange, persistent thoughts, behaviors and emotions. While everyone’s experience is different, most people say psychosis is frightening and confusing.

It’s important to know that psychosis is a symptom, not a specific illness, and can be one of the symptoms of several different illnesses. It’s also more common than you may think. Research suggests that 15-100 people out of 100,000 develop psychosis each year.

Early or first episode (FEP) refers to when a person first shows signs of losing contact with reality. Be aware that the term “first episode” does not mean that there will be additional episodes in the future. What it does mean is that we need to act quickly. Connecting a person with the right treatment during early psychosis or FEP can be life-changing and radically alter that person’s future. Don’t wait to take the first step and prepare yourself with information by reviewing these tip sheets:

What is Early and First-Episode Psychosis?
Early Psychosis: What’s Going on and What Can You Do?
Encouraging People to Seek Help for Early Psychosis
Early Intervention: Tips for School Staff and Coaches

Causes

There is still much that we don’t understand about why psychotic symptoms occur, but research continues to show that there are likely several factors involved. What we do know is that while teenagers and young adults are at increased risk of experiencing an episode of psychosis, it can actually occur at any age.

There are a number of different contributors to the development of these symptoms. A few of the more well known include:

  • Genetics. Many different genes can contribute to the development of psychosis, but just because a person has one of those genes doesn’t mean they will necessarily experience psychosis. Ongoing studies will help us better understand which genes play a role in psychosis for some people but not for others.
  • Trauma. A traumatic event such as a death, war or sexual assault can also be involved in an episode of psychosis. The type of trauma — and a person’s age — affects whether a traumatic event will result in psychosis.
  • Substance use. The use of some substances – such as marijuana, LSD, or amphetamines – can increase the risk of psychosis in people who are already vulnerable.
  • Physical illness or injury. Traumatic brain injuries, brain tumors, strokes, HIV and some brain diseases such as Parkinson’s, Alzheimer’s and dementia can sometimes contribute to the development of psychosis.
  • Mental health conditions. Sometimes psychosis is one of the symptoms of a condition like schizophrenia, schizoaffective disorder, bipolar disorder or depression.

Related Conditions

Psychosis can also occur as part of several different mental health . Each will require a customized treatment plan that integrates these co-occurring conditions. Some of the more common mental health conditions that can include psychosis symptoms are:

Personal Perspectives on Early Psychosis

In this 2-part podcast series, NAMI Chief Medical Officer Dr. Ken Duckworth guides discussions on early psychosis that offer insights from individuals, family members and mental health professionals. Read the transcript.
Note: Content includes discussions on topics such as suicide attempts and may be triggering.

 

Reviewed and updated December 2025

NAMI HelpLine is available M-F, 10 a.m. – 10 p.m. ET. Call 800-950-6264,
text “NAMI” to 62640, or email. In a crisis, call or text 988 (24/7).