This document provides a review of the available research regarding the implementation and impact of co-responder team programs across several communities. This review is organized into four sections. First, the definition and implementation of the co-responder team model are presented. Second, the impact of co-responder team programs on individuals in crisis, the criminal justice system, and the health care system is examined. Next, stakeholders’ perceptions of co-responder team programs and opinions on the elements that make these programs successful are considered. Finally, the implications for future research and practice are reviewed.