||Effects with psychotropic Medications
- Ten percent are poor metabolizers; one to two percent are slow metabolizers
|Latino & Hispanic
- Tend to under-use mental health services and to seek non-psychiatric physicians, expressing more somatic (body) complaints than psychological
- 5% of this population are fast metabolizers; as a result they have very low drug levels in their blood. More research is needed.
- May need lower doses of the antipsychotics Clozaril and Risperdal; U.S. Hispanics respond better to lower dosages of antidepressants
- Rely less on mental health services, instead using social support systems, prayer, folk remedies, etc.
- 33% are slower metabolizers of psychotropic medications when compared to Caucasians and therefore have higher risks for side effects
- Respond more rapidly to neuroleptics and tricyclic antidepressants (TCAs) than Caucasians
- Keep higher plasma levels per dose of TCA and show more side effects; therefore, may need lower dosage
- Frequently reported to be receiving higher doses of neuroleptics, as well as more use of depot neuroleptics
- Have a higher red blood cell/plasma lithium ratio than Caucasians when under treatment for bipolar disorder. More side effects of lithium are reported, which suggests lower doses of lithium therapy may be needed.
- More often view mental illness as stigmatizing, so delay psychiatric care until illnesses are severe; often have more somatic (body) complaints, and try alternative remedies first
- Chinese patients metabolize Haldol quickly so higher plasma levels may occur, along with increased risk of extra-pyramidal side effects (EPS).
- May respond better to lower doses of some medications
- Asians respond to lower doses of lithium
- Chinese patients require lower doses of antipsychotics
- U.S. Asians may respond better to lower doses of antidepressants
- Chinese patients tend to complain less about weight gain and more if drowsiness or impaired memory compromises work performance